Potential point-of-care microfluidic devices to diagnose iron deficiency anemia

Boon Kar Yap, Siti Nur’Arifah M. Soair, Noor Azrina Talik, Wai Feng Lim, I. Lai Mei

Research output: Contribution to journalReview article

Abstract

Over the past 20 years, rapid technological advancement in the field of microfluidics has produced a wide array of microfluidic point-of-care (POC) diagnostic devices for the healthcare industry. However, potential microfluidic applications in the field of nutrition, specifically to diagnose iron deficiency anemia (IDA) detection, remain scarce. Iron deficiency anemia is the most common form of anemia, which affects billions of people globally, especially the elderly, women, and children. This review comprehensively analyzes the current diagnosis technologies that address anemia-related IDA-POC microfluidic devices in the future. This review briefly highlights various microfluidics devices that have the potential to detect IDA and discusses some commercially available devices for blood plasma separation mechanisms. Reagent deposition and integration into microfluidic devices are also explored. Finally, we discuss the challenges of insights into potential portable microfluidic systems, especially for remote IDA detection.

Original languageEnglish
Article number2625
JournalSensors (Switzerland)
Volume18
Issue number8
DOIs
Publication statusPublished - 10 Aug 2018

Fingerprint

Lab-On-A-Chip Devices
Point-of-Care Systems
anemias
Iron-Deficiency Anemias
microfluidic devices
Microfluidics
Iron
iron
Anemia
Equipment and Supplies
Health Care Sector
nutrition
blood plasma
Nutrition
Technology
reagents
Blood
industries

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Atomic and Molecular Physics, and Optics
  • Biochemistry
  • Instrumentation
  • Electrical and Electronic Engineering

Cite this

Yap, Boon Kar ; Soair, Siti Nur’Arifah M. ; Talik, Noor Azrina ; Lim, Wai Feng ; Lai Mei, I. / Potential point-of-care microfluidic devices to diagnose iron deficiency anemia. In: Sensors (Switzerland). 2018 ; Vol. 18, No. 8.
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Potential point-of-care microfluidic devices to diagnose iron deficiency anemia. / Yap, Boon Kar; Soair, Siti Nur’Arifah M.; Talik, Noor Azrina; Lim, Wai Feng; Lai Mei, I.

In: Sensors (Switzerland), Vol. 18, No. 8, 2625, 10.08.2018.

Research output: Contribution to journalReview article

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AU - Yap, Boon Kar

AU - Soair, Siti Nur’Arifah M.

AU - Talik, Noor Azrina

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AU - Lai Mei, I.

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AB - Over the past 20 years, rapid technological advancement in the field of microfluidics has produced a wide array of microfluidic point-of-care (POC) diagnostic devices for the healthcare industry. However, potential microfluidic applications in the field of nutrition, specifically to diagnose iron deficiency anemia (IDA) detection, remain scarce. Iron deficiency anemia is the most common form of anemia, which affects billions of people globally, especially the elderly, women, and children. This review comprehensively analyzes the current diagnosis technologies that address anemia-related IDA-POC microfluidic devices in the future. This review briefly highlights various microfluidics devices that have the potential to detect IDA and discusses some commercially available devices for blood plasma separation mechanisms. Reagent deposition and integration into microfluidic devices are also explored. Finally, we discuss the challenges of insights into potential portable microfluidic systems, especially for remote IDA detection.

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