Performance of STAR virtual trials for diabetic and non-diabetic in HTAA intensive care unit

Ummu K. Jamaludin, Fatimah Dzaharudin, Normy Norfiza Abdul Razak, H. M. Luqman, W. Zuhriraihan W.M. Zulkifly, Fatanah M. Suhaimi, Azrina Md Ralib, Mohd Basri Mat Nor, Christopher G. Pretty

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

Critically ill patients are commonly linked to stress-induced hyperglycaemia which relates to insulin resistance and the risk of per-diagnosed with diabetes and other metabolic illnesses. Thus, it is essential to choose the best practice of blood glucose management in order to reduce morbidity and mortality rates in intensive care unit. This study is focusing on clinical data of 210 critically ill patients in Hospital Tengku Ampuan Afzan (HTAA), Kuantan who underwent Intensive Insulin Therapy which utilized a sliding scale method. Patients were identified in two main groups of diabetic (123) and non-diabetic (87) where stochastic model is generated to observe 90% confidence interval of insulin sensitivity. Blood glucose levels comparison between these two cohorts is conducted to observe the percentage of blood glucose levels within targeted band of 4.4-10.0 mmol/L. It is found that 82% of BG levels are within tar gated band for non-diabetes cohort under stochastic targeted (STAR) glycaemic control protocol. However, only 59.6% and 70.6% BG levels are within targeted band for diabetes cohort for insulin infusion therapy used in HTAA and STAR protocols. Thus, further investigation on blood glucose control protocol for diabetes patients is required to increase the reliability and efficacy of current practice despite of patient safety.

Original languageEnglish
Title of host publicationIECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages193-198
Number of pages6
ISBN (Electronic)9781467377911
DOIs
Publication statusPublished - 01 Jan 2016
Event2016 IEEE-EMBS Conference on Biomedical Engineering and Sciences, IECBES 2016 - Kuala Lumpur, Malaysia
Duration: 04 Dec 201608 Dec 2016

Publication series

NameIECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences

Other

Other2016 IEEE-EMBS Conference on Biomedical Engineering and Sciences, IECBES 2016
CountryMalaysia
CityKuala Lumpur
Period04/12/1608/12/16

Fingerprint

Intensive care units
Insulin
insulin
Glucose
Blood
Medical problems
glucose
blood
therapy
hyperglycemia
Tar
Stochastic models
tars
mortality
sliding
confidence
safety
intervals
sensitivity

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Instrumentation

Cite this

Jamaludin, U. K., Dzaharudin, F., Abdul Razak, N. N., Luqman, H. M., Zulkifly, W. Z. W. M., Suhaimi, F. M., ... Pretty, C. G. (2016). Performance of STAR virtual trials for diabetic and non-diabetic in HTAA intensive care unit. In IECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences (pp. 193-198). [7843441] (IECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/IECBES.2016.7843441
Jamaludin, Ummu K. ; Dzaharudin, Fatimah ; Abdul Razak, Normy Norfiza ; Luqman, H. M. ; Zulkifly, W. Zuhriraihan W.M. ; Suhaimi, Fatanah M. ; Ralib, Azrina Md ; Nor, Mohd Basri Mat ; Pretty, Christopher G. / Performance of STAR virtual trials for diabetic and non-diabetic in HTAA intensive care unit. IECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences. Institute of Electrical and Electronics Engineers Inc., 2016. pp. 193-198 (IECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences).
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abstract = "Critically ill patients are commonly linked to stress-induced hyperglycaemia which relates to insulin resistance and the risk of per-diagnosed with diabetes and other metabolic illnesses. Thus, it is essential to choose the best practice of blood glucose management in order to reduce morbidity and mortality rates in intensive care unit. This study is focusing on clinical data of 210 critically ill patients in Hospital Tengku Ampuan Afzan (HTAA), Kuantan who underwent Intensive Insulin Therapy which utilized a sliding scale method. Patients were identified in two main groups of diabetic (123) and non-diabetic (87) where stochastic model is generated to observe 90{\%} confidence interval of insulin sensitivity. Blood glucose levels comparison between these two cohorts is conducted to observe the percentage of blood glucose levels within targeted band of 4.4-10.0 mmol/L. It is found that 82{\%} of BG levels are within tar gated band for non-diabetes cohort under stochastic targeted (STAR) glycaemic control protocol. However, only 59.6{\%} and 70.6{\%} BG levels are within targeted band for diabetes cohort for insulin infusion therapy used in HTAA and STAR protocols. Thus, further investigation on blood glucose control protocol for diabetes patients is required to increase the reliability and efficacy of current practice despite of patient safety.",
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Jamaludin, UK, Dzaharudin, F, Abdul Razak, NN, Luqman, HM, Zulkifly, WZWM, Suhaimi, FM, Ralib, AM, Nor, MBM & Pretty, CG 2016, Performance of STAR virtual trials for diabetic and non-diabetic in HTAA intensive care unit. in IECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences., 7843441, IECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences, Institute of Electrical and Electronics Engineers Inc., pp. 193-198, 2016 IEEE-EMBS Conference on Biomedical Engineering and Sciences, IECBES 2016, Kuala Lumpur, Malaysia, 04/12/16. https://doi.org/10.1109/IECBES.2016.7843441

Performance of STAR virtual trials for diabetic and non-diabetic in HTAA intensive care unit. / Jamaludin, Ummu K.; Dzaharudin, Fatimah; Abdul Razak, Normy Norfiza; Luqman, H. M.; Zulkifly, W. Zuhriraihan W.M.; Suhaimi, Fatanah M.; Ralib, Azrina Md; Nor, Mohd Basri Mat; Pretty, Christopher G.

IECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences. Institute of Electrical and Electronics Engineers Inc., 2016. p. 193-198 7843441 (IECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Jamaludin UK, Dzaharudin F, Abdul Razak NN, Luqman HM, Zulkifly WZWM, Suhaimi FM et al. Performance of STAR virtual trials for diabetic and non-diabetic in HTAA intensive care unit. In IECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences. Institute of Electrical and Electronics Engineers Inc. 2016. p. 193-198. 7843441. (IECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences). https://doi.org/10.1109/IECBES.2016.7843441