Performance of glycemic control protocol and virtual trial

Fatanah M. Suhaimi, Ummu K. Jamaludin, Normy Norfiza Abdul Razak, Azrina M. Ralib, Mohd Basri Mat Nor

Research output: Contribution to journalArticle

Abstract

Model-based glycemic control offers direct management of patient-specific variability and better adaptive control. Implementation of the model-based glycemic control has the potential to reduce hyperglycemia episodes, mortality and morbidity as seen in some successful TGC. The design of any TGC must consider not only the glycemic target range but also safety and efficacy of the insulin therapy. This paper presents the evaluation of glycemic control protocol adapted in the ICU of Tengku Ampuan Afzan Hospital. Virtual trials method is used to simulate the controller algorithm on a virtual patient with feed variation factor. Data from actual clinical and the virtual trial are compared to analyze the protocol performance concerning blood glucose outcome and insulin efficacy. A stochastic model is also used to indicate metabolic response and metabolic variation of the cohort.

Original languageEnglish
Pages (from-to)5415-5418
Number of pages4
JournalAdvanced Science Letters
Volume23
Issue number6
DOIs
Publication statusPublished - 01 Jan 2017

Fingerprint

Clinical Protocols
Model-based Control
Insulin
Efficacy
Hyperglycemia
performance
Blood Glucose
Morbidity
Clinical Trials
morbidity
Glucose
Safety
Mortality
Intensive care units
Adaptive Control
Therapy
Stochastic Model
Blood
glucose
Stochastic models

All Science Journal Classification (ASJC) codes

  • Computer Science(all)
  • Health(social science)
  • Mathematics(all)
  • Education
  • Environmental Science(all)
  • Engineering(all)
  • Energy(all)

Cite this

Suhaimi, F. M., Jamaludin, U. K., Abdul Razak, N. N., Ralib, A. M., & Nor, M. B. M. (2017). Performance of glycemic control protocol and virtual trial. Advanced Science Letters, 23(6), 5415-5418. https://doi.org/10.1166/asl.2017.7389
Suhaimi, Fatanah M. ; Jamaludin, Ummu K. ; Abdul Razak, Normy Norfiza ; Ralib, Azrina M. ; Nor, Mohd Basri Mat. / Performance of glycemic control protocol and virtual trial. In: Advanced Science Letters. 2017 ; Vol. 23, No. 6. pp. 5415-5418.
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Suhaimi, FM, Jamaludin, UK, Abdul Razak, NN, Ralib, AM & Nor, MBM 2017, 'Performance of glycemic control protocol and virtual trial', Advanced Science Letters, vol. 23, no. 6, pp. 5415-5418. https://doi.org/10.1166/asl.2017.7389

Performance of glycemic control protocol and virtual trial. / Suhaimi, Fatanah M.; Jamaludin, Ummu K.; Abdul Razak, Normy Norfiza; Ralib, Azrina M.; Nor, Mohd Basri Mat.

In: Advanced Science Letters, Vol. 23, No. 6, 01.01.2017, p. 5415-5418.

Research output: Contribution to journalArticle

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