Introducing variational iteration method to a biochemical reaction model

Su Mei Goh, M. S.M. Noorani, I. Hashim

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A basic enzyme kinetics is used to test the effectiveness of an analytical method, called the variational iteration method (VIM). This enzymesubstrate reaction is formed by a system of nonlinear ordinary differential equations. We shall compare the classical VIM against a modified version called the multistage VIM (MVIM). Additional comparison will be made against the conventional numerical method, RungeKutta (RK4)(fourth-order). Numerical results were obtained for these three methods and we found that MVIM and RK4 are in excellent conformance.

Original languageEnglish
Pages (from-to)2264-2272
Number of pages9
JournalNonlinear Analysis: Real World Applications
Issue number4
Publication statusPublished - 01 Aug 2010


All Science Journal Classification (ASJC) codes

  • Analysis
  • Engineering(all)
  • Economics, Econometrics and Finance(all)
  • Computational Mathematics
  • Applied Mathematics

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