Insulin sensitivity and blood glucose level of sepsis patients in the intensive care unit

Fatanah M. Suhaimi, Ummu K. Jamaludin, Normy Norfiza Abdul Razak, Mohd Basri Mat Nor, Azrina M. Ralib, Wan Fadzlina Wan Muhd Shukeri, Mohd Shahnaz Hasan, Asma Abu-Samah, Nizuwan Azman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Sepsis and hyperglycemia are highly associated with increases in mortality rates, particularly in the critically ill patients. Sepsis diagnosis has been proven challenging due to delay in getting the blood culture results. Thus, often clinical experiences overrule the protocol to prevent the worsening outcome of the patients. In some cases, the erroneous clinical judgement cause antibiotic resistance and even adverse clinical outcomes. This paper investigates the correlation between two parameters; insulin sensitivity and blood glucose level among sepsis patients. The blood glucose level is measured at the bedside during the patient’s stay, whereas insulin sensitivity is obtained using the validated glucose-insulin model. Thus, the insulin sensitivity is a specific parameter of the patient, unregimented of the protocol given to the patient. The same parameters, blood glucose and insulin sensitivity, are also compared to the non-sepsis patients to establish a relationship that can be used for sepsis diagnosis. Given the availability of these two parameters that can be captured rapidly and instantly, a significant relationship can, therefore, help clinicians to identify sepsis at an early stage without second-guessing.

Original languageEnglish
Title of host publication2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages265-269
Number of pages5
ISBN (Electronic)9781538624715
DOIs
Publication statusPublished - 24 Jan 2019
Event2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Kuching, Malaysia
Duration: 03 Dec 201806 Dec 2018

Publication series

Name2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings

Conference

Conference2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018
CountryMalaysia
CityKuching
Period03/12/1806/12/18

Fingerprint

Intensive care units
insulin
Insulin
glucose
blood
Intensive Care Units
Glucose
Insulin Resistance
Blood Glucose
Sepsis
Blood
sensitivity
hyperglycemia
Antibiotics
antibiotics
mortality
Microbial Drug Resistance
guy wires
Availability
Critical Illness

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Medicine (miscellaneous)
  • Health Informatics
  • Instrumentation

Cite this

Suhaimi, F. M., Jamaludin, U. K., Abdul Razak, N. N., Nor, M. B. M., Ralib, A. M., Shukeri, W. F. W. M., ... Azman, N. (2019). Insulin sensitivity and blood glucose level of sepsis patients in the intensive care unit. In 2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings (pp. 265-269). [08626722] (2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/IECBES.2018.08626722
Suhaimi, Fatanah M. ; Jamaludin, Ummu K. ; Abdul Razak, Normy Norfiza ; Nor, Mohd Basri Mat ; Ralib, Azrina M. ; Shukeri, Wan Fadzlina Wan Muhd ; Hasan, Mohd Shahnaz ; Abu-Samah, Asma ; Azman, Nizuwan. / Insulin sensitivity and blood glucose level of sepsis patients in the intensive care unit. 2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2019. pp. 265-269 (2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings).
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Suhaimi, FM, Jamaludin, UK, Abdul Razak, NN, Nor, MBM, Ralib, AM, Shukeri, WFWM, Hasan, MS, Abu-Samah, A & Azman, N 2019, Insulin sensitivity and blood glucose level of sepsis patients in the intensive care unit. in 2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings., 08626722, 2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings, Institute of Electrical and Electronics Engineers Inc., pp. 265-269, 2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018, Kuching, Malaysia, 03/12/18. https://doi.org/10.1109/IECBES.2018.08626722

Insulin sensitivity and blood glucose level of sepsis patients in the intensive care unit. / Suhaimi, Fatanah M.; Jamaludin, Ummu K.; Abdul Razak, Normy Norfiza; Nor, Mohd Basri Mat; Ralib, Azrina M.; Shukeri, Wan Fadzlina Wan Muhd; Hasan, Mohd Shahnaz; Abu-Samah, Asma; Azman, Nizuwan.

2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2019. p. 265-269 08626722 (2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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T1 - Insulin sensitivity and blood glucose level of sepsis patients in the intensive care unit

AU - Suhaimi, Fatanah M.

AU - Jamaludin, Ummu K.

AU - Abdul Razak, Normy Norfiza

AU - Nor, Mohd Basri Mat

AU - Ralib, Azrina M.

AU - Shukeri, Wan Fadzlina Wan Muhd

AU - Hasan, Mohd Shahnaz

AU - Abu-Samah, Asma

AU - Azman, Nizuwan

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N2 - Sepsis and hyperglycemia are highly associated with increases in mortality rates, particularly in the critically ill patients. Sepsis diagnosis has been proven challenging due to delay in getting the blood culture results. Thus, often clinical experiences overrule the protocol to prevent the worsening outcome of the patients. In some cases, the erroneous clinical judgement cause antibiotic resistance and even adverse clinical outcomes. This paper investigates the correlation between two parameters; insulin sensitivity and blood glucose level among sepsis patients. The blood glucose level is measured at the bedside during the patient’s stay, whereas insulin sensitivity is obtained using the validated glucose-insulin model. Thus, the insulin sensitivity is a specific parameter of the patient, unregimented of the protocol given to the patient. The same parameters, blood glucose and insulin sensitivity, are also compared to the non-sepsis patients to establish a relationship that can be used for sepsis diagnosis. Given the availability of these two parameters that can be captured rapidly and instantly, a significant relationship can, therefore, help clinicians to identify sepsis at an early stage without second-guessing.

AB - Sepsis and hyperglycemia are highly associated with increases in mortality rates, particularly in the critically ill patients. Sepsis diagnosis has been proven challenging due to delay in getting the blood culture results. Thus, often clinical experiences overrule the protocol to prevent the worsening outcome of the patients. In some cases, the erroneous clinical judgement cause antibiotic resistance and even adverse clinical outcomes. This paper investigates the correlation between two parameters; insulin sensitivity and blood glucose level among sepsis patients. The blood glucose level is measured at the bedside during the patient’s stay, whereas insulin sensitivity is obtained using the validated glucose-insulin model. Thus, the insulin sensitivity is a specific parameter of the patient, unregimented of the protocol given to the patient. The same parameters, blood glucose and insulin sensitivity, are also compared to the non-sepsis patients to establish a relationship that can be used for sepsis diagnosis. Given the availability of these two parameters that can be captured rapidly and instantly, a significant relationship can, therefore, help clinicians to identify sepsis at an early stage without second-guessing.

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U2 - 10.1109/IECBES.2018.08626722

DO - 10.1109/IECBES.2018.08626722

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BT - 2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings

PB - Institute of Electrical and Electronics Engineers Inc.

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Suhaimi FM, Jamaludin UK, Abdul Razak NN, Nor MBM, Ralib AM, Shukeri WFWM et al. Insulin sensitivity and blood glucose level of sepsis patients in the intensive care unit. In 2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2019. p. 265-269. 08626722. (2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings). https://doi.org/10.1109/IECBES.2018.08626722